Abstract
Palladium-catalyzed cross-coupling of a wide range of substituted o-(pseudo)halobenzoates and hydrazines with isocyanide insertion followed by lactamization efficiently affords 4-aminophthalazin-1(2H)-ones that are difficult to obtain regioselectively by classical methods.
Original language | English |
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Pages (from-to) | 6496-6499 |
Number of pages | 4 |
Journal | Organic letters |
Volume | 13 |
Issue number | 24 |
DOIs | |
Publication status | Published - 15 Nov 2011 |
Keywords
- Catalysis
- Molecular Structure
- Nitriles/chemistry
- Palladium/chemistry
- Phthalazines/chemical synthesis
- Stereoisomerism