Toxicokinetics and bioconcentration of polycyclic aromatic hydrocarbons in freshwater isopods

A.G.M. van Hattum, J.F. Cid Montañés

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Abstract

A novel method based on a first-order two-compartment model was used to determine the bioconcentration and toxicokinetic rate constants of six different polycyclic aromatic hydrocarbons (PAHs) in the freshwater isopod Asellus aquaticus, a common species in most European freshwater systems. Numerical integration and iterative parameter estimation techniques were applied to account for time-varying aqueous exposure concentrations. All PAHs exhibited a rapid uptake. Monophasic elimination patterns were observed for benzo[e]pyrene and benzo[a]-pyrene (biological half-life t
Original languageEnglish
Pages (from-to)2409-2417
JournalEnvironmental Science and Technology
Volume33
DOIs
Publication statusPublished - 1999

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