Abstract
A series of 3-phenyl-3H-quinazolin-4-ones have been synthesized and tested for affinity and activity at the chemokine CXCR3 receptor. The most potent compound (1d) has been evaluated using radioligand binding and calcium mobilization assays and is considered a useful tool for further characterization of the CXCR3 receptor. © 2005 Elsevier Ltd. All rights reserved.
Original language | English |
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Pages (from-to) | 2910-3 |
Journal | Bioorganic and Medicinal Chemistry Letters |
Volume | 15 |
Issue number | 11 |
DOIs | |
Publication status | Published - 2005 |