TY - JOUR
T1 - Impairment of complex upper limb motor function in de novo parkinson's disease.
AU - Ponsen, M.M.
AU - Daffertshofer, A.
AU - Wolters, E.C.M.J.
AU - Beek, P.J.
AU - Berendse, H.W.
PY - 2008
Y1 - 2008
N2 - The aim of the present study was to evaluate complex upper limb motor function in newly diagnosed, untreated Parkinson's disease (PD) patients. Four different unimanual upper limb motor tasks were applied to 13 newly diagnosed, untreated PD patients and 13 age- and sex-matched controls. In a handwriting task, PD patients had significantly reduced sentence length and writing velocity, and decreasing letter height in the course of writing. Furthermore, PD patients performed an aiming task slower with than without target, and showed increased transposition in a pointing task. The results of this study extend previous observations of impaired complex upper limb movements to newly diagnosed, untreated PD patients. © 2007 Elsevier Ltd. All rights reserved.
AB - The aim of the present study was to evaluate complex upper limb motor function in newly diagnosed, untreated Parkinson's disease (PD) patients. Four different unimanual upper limb motor tasks were applied to 13 newly diagnosed, untreated PD patients and 13 age- and sex-matched controls. In a handwriting task, PD patients had significantly reduced sentence length and writing velocity, and decreasing letter height in the course of writing. Furthermore, PD patients performed an aiming task slower with than without target, and showed increased transposition in a pointing task. The results of this study extend previous observations of impaired complex upper limb movements to newly diagnosed, untreated PD patients. © 2007 Elsevier Ltd. All rights reserved.
U2 - 10.1016/j.parkreldis.2007.07.019
DO - 10.1016/j.parkreldis.2007.07.019
M3 - Article
SN - 1353-8020
VL - 14
SP - 199
EP - 204
JO - Parkinsonism and Related Disorders
JF - Parkinsonism and Related Disorders
IS - 3
ER -