Impairment of complex upper limb motor function in de novo parkinson's disease.

M.M. Ponsen, A. Daffertshofer, E.C.M.J. Wolters, P.J. Beek, H.W. Berendse

    Research output: Contribution to JournalArticleAcademicpeer-review

    Abstract

    The aim of the present study was to evaluate complex upper limb motor function in newly diagnosed, untreated Parkinson's disease (PD) patients. Four different unimanual upper limb motor tasks were applied to 13 newly diagnosed, untreated PD patients and 13 age- and sex-matched controls. In a handwriting task, PD patients had significantly reduced sentence length and writing velocity, and decreasing letter height in the course of writing. Furthermore, PD patients performed an aiming task slower with than without target, and showed increased transposition in a pointing task. The results of this study extend previous observations of impaired complex upper limb movements to newly diagnosed, untreated PD patients. © 2007 Elsevier Ltd. All rights reserved.
    Original languageEnglish
    Pages (from-to)199-204
    JournalParkinsonism and Related Disorders
    Volume14
    Issue number3
    DOIs
    Publication statusPublished - 2008

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