A treatment planning study evaluating a 'simultaneous integrated boost' technique for accelerated radiotherapy of stage III non-small cell lung cancer.
Sornsen de Koste, J.R. van
MetadataShow full item record
20 Gy by 2% on average. Although the length and volume of oesophagus irradiated to at least 50 Gy increased for some of the patients, the observed values were less than that was the case for the actual delivered treatment. However, special care should be taken to avoid exceeding the spinal cord tolerance in patients whose tumours are located close to the cord. CONCLUSIONS: A SIB technique that delivers at least 50 Gy to the pre-chemotherapy tumour volume permits accelerated radiotherapy in patients with stage III NSCLC without increasing the expected risks of normal tissue toxicity. By reducing the overall treatment time, the SIB technique may improve local tumour control and survival.