Abstract
Cytochromes P450 (P450s) constitute a large superfamily of heme- containing enzymes, capable of oxidizing and reducing a variety of substrates. Cytochrome P450 2D6 is a polymorphic member of the P450 superfamily and is absent in 5-9% of the Caucasian population as a result of a recessive inheritance of gene mutations. Recently, the importance of aspartic acid 301 (Asp
Original language | English |
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Pages (from-to) | 41-48 |
Journal | Chemical Research in Toxicology |
Volume | 10 |
DOIs | |
Publication status | Published - 1997 |