The ribosome and YidC: new insights into the biogenesis of Escherichia coli inner membrane proteins.

J.-W. de Gier, S. Luirink

    Research output: Contribution to JournalArticleAcademic

    Abstract

    In the bacterium Escherichia coli, inner membrane proteins (IMPs) are generally targeted through the signal recognition particle pathway to the Sec translocon, which is capable of both linear transport into the periplasm and lateral transport into the lipid bilayer. Lateral transport seems to be assisted by the IMP YidC. in this article, we discuss recent observations that point to a key role for the ribosome in IMP targeting and to the diverse roles of YidC in IMP assembly.
    Original languageEnglish
    Pages (from-to)939-943
    Number of pages5
    JournalEMBO Reports
    Volume4
    DOIs
    Publication statusPublished - 2003

    Fingerprint

    Dive into the research topics of 'The ribosome and YidC: new insights into the biogenesis of Escherichia coli inner membrane proteins.'. Together they form a unique fingerprint.

    Cite this