The Genetic and Environmental Contributions to Oppositional Defiant Behavior: a Multi-informant Twin Study

J. Hudziak, E.M. Derks, R. Althoff, W. Copeland, D.I. Boomsma

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Objective: To estimate the genetic and environmental contributions to oppositional defiant behavior (ODB) from mother, father, and teacher report using the Conners Revised Short Forms in a large twin sample. Method: ODB data were collected from 1,595 mothers, 1,114 fathers, and 793 teachers of 7-year-old twin pairs from the Netherlands Twin Registry in the 1990-1992 cohort with an 80% response rate. Models were fit for each informant to determine the genetic, environmental, gender, and informant influences on ODB. Results: Genetic analyses of the ODB quantitative scale showed additive genetic (A) by mother (55%), by father (57%), and by teacher (21% girls, 38% boys) unique environmental (E) (mother, 22%; father, 29%; teacher, 48% girls, 39% boys) and shared environmental (C) (mother, 14%; father, 23%; teacher, 31% girls, 23% boys) influences. Conclusions: Additive genetic and unique environmental factors account for the majority of the influences on ODB for boys and girls by all informants. ©2005 by the American Academy of Child and Adolescent Psychiatry.
Original languageEnglish
Pages (from-to)907-914
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Volume44
Issue number9
DOIs
Publication statusPublished - 2005

Cohort Studies

  • Netherlands Twin Register (NTR)

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