TY - JOUR
T1 - Deficits in visuo-spatial working memory, inhibition and oculomotor control in boys with ADHD and their non-affected brothers
AU - Rommelse, N.N.J.
AU - van der Stigchel, S.
AU - Witlox, J.
AU - Geldof, C.J.A.
AU - Deijen, J.B.
AU - Theeuwes, J.
AU - Oosterlaan, J.
AU - Sergeant, J.A.
PY - 2008/2
Y1 - 2008/2
N2 - Few studies have assessed visuo-spatial working memory and inhibition in attention-deficit/hyperactivity disorder (ADHD) by recording saccades and consequently little additional knowledge has been gathered on oculomotor functioning in ADHD. Moreover, this is the first study to report the performance of non-affected siblings of children with ADHD, which may shed light on the familiality of deficits. A total of 14 boys with ADHD, 18 non-affected brothers, and 15 control boys aged 7-14 years, were administered a memory-guided saccade task with delays of three and seven seconds. Familial deficits were found in accuracy of visuo-spatial working memory, percentage of anticipatory saccades, and tendency to overshoot saccades relative to controls. These findings suggest memory-guided saccade deficits may relate to a familial predisposition for ADHD. © 2008 Springer-Verlag.
AB - Few studies have assessed visuo-spatial working memory and inhibition in attention-deficit/hyperactivity disorder (ADHD) by recording saccades and consequently little additional knowledge has been gathered on oculomotor functioning in ADHD. Moreover, this is the first study to report the performance of non-affected siblings of children with ADHD, which may shed light on the familiality of deficits. A total of 14 boys with ADHD, 18 non-affected brothers, and 15 control boys aged 7-14 years, were administered a memory-guided saccade task with delays of three and seven seconds. Familial deficits were found in accuracy of visuo-spatial working memory, percentage of anticipatory saccades, and tendency to overshoot saccades relative to controls. These findings suggest memory-guided saccade deficits may relate to a familial predisposition for ADHD. © 2008 Springer-Verlag.
U2 - 10.1007/s00702-007-0865-7
DO - 10.1007/s00702-007-0865-7
M3 - Article
SN - 0300-9564
VL - 115
SP - 249
EP - 260
JO - Journal of Neural Transmission
JF - Journal of Neural Transmission
IS - 2
ER -